HPP REAL STORIES

Meet Tanner

Diagnosed with HPP at 4 days old

When Tanner was born, his mother, René, did not suspect anything was wrong with him. Then his doctors noticed that his wrists were retracting and he had an unusual amount of cartilage.

Tanner, diagnosed with HPP at 4 days old, with a stuffed animal

After his x-rays and blood work were evaluated, Tanner was diagnosed with hypophosphatasia (HPP). His doctors told René that he had a 50 percent chance of survival. She was terrified for her son.

Tanner, diagnosed with HPP at 4 days old, playing on a playground Tanner, diagnosed with HPP at 4 days old, sliding down a slide

A week later, Tanner’s pediatrician called René to tell her about a clinical trial for STRENSIQ® (asfotase alfa). Tanner’s health was declining and without an approved therapy for HPP, René felt that the clinical trial was the best option for her son. The family flew several hundred miles from Missouri to the clinical trial site in Delaware. Within a week, Tanner began his infusions and remained under his doctors’ supervision for the next five months.

Several years later, Tanner is still doing well and continues to receive treatment with STRENSIQ.* “As Tanner has gotten old the clinical trial has helped him grow. He can walk. He tries to be very big and helpful,” René shared. “My hope for Tanner in the future is that he enters into adulthood. I think that he's very smart, and I think that he is definitely going to go to college. I kind of hope that he will be a doctor, and maybe help kids like doctors have helped him.”

*The results from use of STRENSIQ may vary.


IMPORTANT SAFETY INFORMATION

What is Strensiq® (asfotase alfa)?
Strensiq is a prescription medicine used to treat people with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

What are the possible side effects of Strensiq?
Strensiq may cause serious side effects, including

  • Serious allergic (hypersensitivity) reactions. Serious allergic reactions have happened in some people who use Strensiq. Stop using Strensiq and go to the nearest hospital emergency room right away if you have any of the signs and symptoms of a serious allergic reaction, including
    • Difficulty breathing
    • Swelling of your eyes, lips, or tongue
    • Hives
    • Feeling faint
    • Nausea or vomiting
    • Dizziness
    • Itching of your lips, tongue, or throat
    • Choking sensation
  • Skin thickening or pits at the injection site (lipodystrophy). Lipodystrophy at the injection site has happened several months after using Strensiq
  • Calcium buildup in your eyes and kidneys. Your healthcare provider should check your eyes and kidneys while you use Strensiq

The most common side effects of Strensiq include local skin injection-site reactions (including red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Tell your doctor if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

These are not all of the possible side effects of Strensiq. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to the US Food and Drug Administration at 1-800-FDA-1088.

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