At Alexion, we commit ourselves every day to delivering on our mission of serving people living with rare diseases. This is especially important during a global health crisis like the current COVID-19 pandemic. We remain focused on continuing to serve the patients who rely on us, as well as protecting the health and safety of our employees and the communities in which we live and work.
Commitment to Patients
The resilience of patients and their families is our inspiration, and the safety of those receiving our medicines and participating in our clinical trials remains paramount. Alexion's goal is always to manage a robust supply chain that delivers medicines that are secure, sterile and meet our rigorous quality standards. In addition, due to the life-saving nature of our medicines, we strive to maintain sufficient inventory levels to ensure their supply to the patients who rely on them. We have taken proactive measures to mitigate the risk of potential interruptions in supply, and we are continuing to actively monitor this dynamic and rapidly evolving situation worldwide.
On January 13, 2021, Alexion announced the decision to pause further enrollment in the global Phase 3 study of ULTOMIRIS® (ravulizumab-cwvz) in adults with severe COVID-19 requiring mechanical ventilation. This decision is based on the recommendation of an independent data monitoring committee (IDMC), following their review of data from a pre-specified interim analysis.
Alexion announced plans to initiate a global Phase 3 study to investigate ULTOMIRIS® (ravulizumab-cwvz) in a subset of adults with COVID-19 – those who are hospitalized with severe pneumonia or acute respiratory distress syndrome (ARDS).
Alexion is committed to assisting communities and medical systems in their efforts to address the public health crisis caused by the COVID-19 pandemic and is taking a holistic approach to supporting our global communities across a range of areas of need.
In early February, in response to the government’s outreach, Alexion reached out to the U.S. Department of Health and Human Services’ Biomedical Advanced Research and Development Authority (BARDA) office, the Department of Defense (DoD) and others within government to discuss the potential use of SOLIRIS® (eculizumab) in patients with COVID-19.
If anything, living with PNH has made me appreciate my time even more, and given me more drive to get back to doing what I love to do.”JOE LIVING WITH PNH