Discovery Partnerships

We’re committed to supporting academic investigators advance their research and develop innovative, life-changing medicines through the collaborative Discovery Partnerships program.

We encourage the submission of proposals focused on preclinical translation of scientific discoveries into therapies for rare disorders.

Please note that Alexion receives many requests for Discovery Partnerships and carefully evaluates each submission on a highly competitive basis. This review process considers, among other things, scientific rigor, translatability and alignment with our strategic priorities, as well as potential redundancy with research efforts.

Areas of Interest

Our core area of focus has been treating complement-mediated diseases. We are always interested in scientific research with high potential to translate into breakthrough therapies for rare diseases outside of our core focus.

Proposals focused on the characterization and/or optimization of a therapeutic candidate (or surrogate molecule), or the validation of novel targets for rare diseases are given priority. Proposals for access to Alexion’s large repertoire of therapeutic surrogates to validate novel indications will also be considered.

Resources from Alexion’s internal Research & Development can be made available to support research work (i.e. antibody engineering, protein purification, bioanalytical assay development). Please specify on your proposal whether you will require any of these capabilities. If you would like more information, please contact

How to Submit a Proposal

Investigators interested in submitting a proposal for consideration will first have to register on Alexion’s web-based system by creating a profile. Once registered, the proposal can be submitted electronically. Please note that e-mail submissions are not accepted and will not be reviewed. To complete your proposal submission, please specify the type of support you are requesting (collaboration funding, research reagents and/or capabilities). The application should assume the form of a grant application with the following information:

  • Project Name
  • Investigator(s), Institutional Affiliation
  • Aims and Hypotheses
  • Background and Preliminary Data (if available)
  • Research Plan (please include milestones and estimated timelines)
  • Expected Outcomes and Significance
  • References
  • Requested Budget and Justification
  • Materials and Resources Requested from Alexion
  • Credentials of Investigator(s) (please use NIH BioSketch guidelines)

A final decision on your application can be returned within ninety (90) days of submission. However, failure to include any of the above information or provide any requested clarifications may result in a delay in the decision.

Submit your discovery partnership proposal

Request assistance with your proposal

VisionTracker Inquiries

USA: +1-860-266-4944

UK & EU: +44 1403 322095

Clinical Research

Clinical research—such as patient natural history, non-interventional biomarker studies, and/or drug intervention studies—will not be considered by Alexion Discovery Partnerships and proposals should be submitted through the Externally-Sponsored Research page. For more information, please contact

Evie, diagnosed with HPP at 2 weeks old, riding a toy car
Her story gives other parents with special needs kids hope that they can be okay, and things can be good.”