Alexion Ireland Page

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Ireland

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Alexion Mission

Pioneering New Possibilities for the Rare Disease Community 

We are driven by a mission to change what it means to live with a rare disease. Built on a legacy of turning pioneering science into transformative treatments, we listen to and partner with the rare disease ecosystem to help improve outcomes for more people impacted by rare diseases across the globe.

Developing breakthrough therapies for rare diseases is only possible because of the tireless efforts of our global community of researchers and scientists, advocates and caregivers, and most important, patients.

As part of AstraZeneca, we have the potential to impact the lives of even more people around the world.

Alexion in Ireland

Ireland has always been an important location for Alexion, having been present there for over 10 years. It is a country we are proud to be associated with and is home to our global manufacturing operations facilities, and our global supply chain.

We employ over 1,300 people across our two state of the art manufacturing facilities in Dublin and Athlone. Our global supply chain works from Ireland to distribute our rare disease therapies throughout the world.

Due to the strategic importance of Ireland within the EU it is also home to multiple global teams which support our commercial and pipeline product lifecycle.

Sustainability

We are committed to sustainability in Ireland, for the local communities, and for our colleagues. We recognise the connection between a healthy planet and healthy people and are committed to proactively managing our environmental impact.

Across our sites we have invested in infrastructure projects utilising new technologies that help reduce water usage and bring in sustainable heat and energy sources. We have also converted our road freight in Ireland and out across the EU to green fuels reducing our road freight carbon emissions by 90%. 

In addition, we work with local environmental groups to support ecology projects across Ireland, recently launching a project to reintroduce Atlantic rain forests to the West Coast of Ireland. These investments will continue as we work towards our goal of being net zero by 2045.

Rare Diseases Supported in Ireland

Alexion works across various rare diseases, including:

Paroxysmal Nocturnal Haemoglobinuria (PNH)

A rare, chronic, progressive and potentially life-threatening blood disorder. It is characterised by red blood cell destruction within blood vessels (also known as intravascular haemolysis) and white blood cell and platelet activation, which can result in thrombosis (blood clots).

Atypical Haemolytic Uraemic Syndrome (aHUS)

A rare disease that can cause progressive injury to vital organs, primarily the kidneys, via damage to the walls of blood vessels and blood clots.

Neurofibromatosis Type 1 (NF1) Plexiform Neurofibromas (PN)

A rare, progressive, genetic condition characterized by non-malignant (non-cancerous) tumors called plexiform neurofibromas (PN) that develop in the brain, and along the spinal cord and nerve.

Generalised Myasthenia Gravis (gMG)

A rare, autoimmune neuromuscular disease characterised by loss of muscle function and severe muscle weakness.

Neuromyelitis Optica Spectrum Disorder (NMOSD)

A rare autoimmune disease of the central nervous system, characterised by unpredictable relapses which can result in cumulative disability.

Hypophosphatasia (HPP)

A rare, inherited, metabolic disease characterized by impaired mineralization (“calcification”), the process that hardens and strengthens bones and teeth. This can lead to poor growth and development, weakness and deformity of bones and other skeletal abnormalities, and premature loss of teeth with the root intact.

Lysosomal Acid Lipase Deficiency (LAL-D)

A genetic, and progressive ultra-rare metabolic disease associated with multiorgan damage in infant, paediatric and adult patients, and premature death in infants.

Medicines

Medicines Licensed in Ireland

For information on medicines licensed in Ireland please click here.

Clinical Trials

Clinical Trials

Alexion is committed to serving people affected by rare diseases through the discovery, development and delivery of life-changing medicines. Our goal is to bring safe and effective medicines to as many patients as possible by conducting rigorous clinical trials and obtaining marketing approval by regulatory authorities around the world. Our work is marked by a commitment to the highest standards of preclinical and clinical research, and an acute sense of urgency. As such, we prioritize access to our investigational medicines through participation in a clinical trial.

To inquire about a clinical trial, please contact

clinicaltrials@alexion.com

Transparency and Disclosure

Alexion is committed to operating with integrity, accountability, and transparency, and to complying with all applicable laws and regulations.

Alexion fully participates in The Irish Pharmaceutical Healthcare Association’s (IPHA) Disclosure of Transfers of Value (ToV) initiative to increase transparency about the relationships we have with doctors, nurses, pharmacists, and other healthcare professionals across Ireland.

Disclosure

Gender Pay Gap

At Alexion we are working hard to support a thriving culture where diversity and inclusion are embraced, and where people can bring their authentic selves to work. As a manufacturing and scientific site, we work with local universities and schools to inspire all young people to consider a STEM career. We’re working hard to close the gender pay gap and are transparent in our reporting.

Careers

Career Opportunities

At Alexion, we foster an environment that attracts and retains the best talent. We provide the tools to enable each individual to perform at their personal best so that we maximize our collective impact.

Explore Careers

Contact Information

Orders & Enquiries

T: UK 0800 1300 212
customeroperationsuk@alexion.com

Adverse Events

T: 1 800 936 544

Medical Information

T: 1 800 882 840

Product Issues

 

Alexion Pharma International Operations Limited

Veeva ID: M/IE/UNB-U/0015

Date of Preparation: March 2026

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