Our Inspiration
- Living With Rare Diseases
- Real Stories
  - NF1
  - aHUS
  - gMG
  - HPP
  - LAL-D
  - NMOSD
  - PNH
- Support Services
Albie, one of our guiding stars

When Albie was born, his mom, Charlotte, said that he was “absolutely fine. Everything was fine for about two weeks.”
Our Medicines
- Conditions We Treat
  - aHUS
  - gMG
  - HPP
  - LAL-D
  - NF1 PN
  - NMOSD
  - PNH
- Medicines
Our medicines help people like Donnan

As a father of two young children, Donnan recalls being afraid of what the future would hold prior to his diagnosis.
Our Research
We innovate for Ruthie

Married with a newborn son, Ruthie was scared to learn that PNH was a life-threatening illness that at the time had no approved treatment.
Our Commitment
We give back for families like Evie's

At only three months old, Evie's parents were told that her case was severe and that there were no approved or effective treatment options.
Our Company
Liz is our inspiration

Although physical challenges required Liz, her husband, and their children to adjust their lives in many ways, she doesn't let her disease hold her back.
Your Career
- Career Opportunities
  - Join Our Team
- Working Here
  - Benefits
  - Culture
Make a difference for families like Tristan's

Tristan's parents experienced a whirlwind of emotions and fear after learning their 5-year-old son had such a rare and serious disease.

LEADERSHIP

Shane Doyle

SVP, Head of Operations

Shane Doyle is Senior Vice President, Global Manufacturing Operations of Alexion, AstraZeneca Rare Disease.

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About Shane

Shane provides strategic leadership to the Global Manufacturing and Engineering organizations, leading global capital programs for the Alexion manufacturing network. Since joining Alexion in 2014, Shane led the development of Ireland-based manufacturing operations at College Park and Athlone, and the Global Operations Engineering team. In 2015, the oversight of manufacturing operations at Contract Manufacturing (CMO) sites was added to his responsibilities. Prior to joining Alexion, Shane spent more than 15 years in manufacturing and engineering roles most recently at Genzyme, and also within Merck, Pfizer, and La Farge UK.

Shane earned his MBA from Smurfit Business School, UCD, Bachelor of Chemical Engineering degree from Cork Institute of Technology, and Bachelor of Science Industrial Chemistry degree from the University of Limerick.

It’s important to me to remain positive. It’s a scary journey and there are unknowns. But from my perspective, I still have my life to live.”

JASON LIVING WITH PNH

LEARN MORE ABOUT PNH

Shane Doyle

SVP, Head of Operations

About Shane

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